Intercellular mechanotransduction during multicellular morphodynamics
نویسندگان
چکیده
منابع مشابه
Intercellular mechanotransduction during multicellular morphodynamics.
Multicellular structures are held together by cell adhesions. Forces that act upon these adhesions play an integral role in dynamically re-shaping multicellular structures during development and disease. Here, we describe different modes by which mechanical forces are transduced in a multicellular context: (i) indirect mechanosensing through compliant substratum, (ii) cytoskeletal 'tug-of-war' ...
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Endothelial cells respond to fluid shear stress through mechanotransduction responses that affect their cytoskeleton and cell-cell contacts. Here, endothelial cells were grown as monolayers on arrays of microposts and exposed to laminar or disturbed flow to examine the relationship among traction forces, intercellular forces, and cell-cell junctions. Cells under laminar flow had traction forces...
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intact animal to the cellular, subcellular, and molecular levels. It is published 12 times a year (monthly) by the American lymphatics, including experimental and theoretical studies of cardiovascular function at all levels of organization ranging from the publishes original investigations on the physiology of the heart, blood vessels, and AJP-Heart and Circulatory Physiology
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2010
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2010.0066.focus